摘要
南极磷虾油具有抗炎功效,但功效成分类型和作用靶点并不明确。本研究精制获得磷虾油抗炎有效部位磷虾轻油乙酯,通过HPLC分析明确其中EPA+DHA乙酯含量>60%,体外抗炎活性结果显示磷虾轻油乙酯具有较强活性,且呈剂量相关,其抗炎作用主要表现为抑制炎症因子NO、IL-6;磷虾极性脂磷脂平均含量达到65%,但抗炎活性微弱。
The Antarctic krill oil has been proved beneficial for treatment of inflammatory disorders, but the types of effective components and targets were not clear.Ethyl ester fraction of light oil from Antarctic krill was obtained in this study, and it has strong anti-inflammatory activity in a dose-dependent manner.Its anti-inflammatory effects mainly acted as inhibition of inflammatory factors NO and IL-6.The relative contents of EPA and DHA ethyl esters are more than 60% by HPLC.The total krill phospholipid fraction has phospholipid contents higher than 65% on average, but showed weak anti-inflammatory activity.
作者
田晓清
常俊男
李月月
陆亚男
樊成奇
TIAN Xiao-qing;CHANG Jun-nan;LI Yue-yue(East China Sea fisheries Research Institute,Chinese Academy of Fishery Sciences,Shanghai 200090;College of Food Sciences & Technology,Shanghai Ocean University,Shanghai 201306,China)
出处
《浙江海洋大学学报（自然科学版）》
CAS
北大核心
2019年第3期205-209,共5页
Journal of Zhejiang Ocean University：Natural Science
基金
中国水产科学研究院中央级公益性科研院所基本科研业务费专项资金(2016HY-ZD0903)
关键词
南极磷虾
磷虾轻油乙酯
抗炎活性
Euphausea superba
EPA and DHA ethyl esters
anti-inflammatory activity
