糜烂性口腔扁平苔藓患者口腔真菌感染因素分析

Influence factors on oral fungal infection for patients with erosive oral lichen planus

目的:了解糜烂型口腔扁平苔藓(oral lichen planus,OLP)患者口腔真菌感染的患病情况,并分析可能的影响因素.方法:纳入糜烂型OLP患者60例,健康志愿者30例,通过口腔真菌涂片检查,比较两组真菌感染患病率;并分析年龄、病程等因素对患病率的影响.结果:糜烂型OLP患者中真菌涂片阳性率显著高于健康志愿者;在年龄>45岁组的阳性率显著高于年龄≤45岁组,且病程>6月的患者的阳性率显著高于病程≤6月的患者.结论:糜烂型OLP患者是口腔真菌感染的高发人群,且年龄大、病程长的患者患病率更高.这类患者的治疗过程中,应重视口腔真菌感染的预防和治疗.

Objective: To investigate the prevalence of oral fungal infection in patients with erosive oral lichen planus (OLP) and analyze the possible influencing factors. Methods:To compare the prevalence of oral fungal infection,60 patients with erosive OLP and 30 healthy volunteers were enrolled, and oral fungal smear examination was performed. The influence of age and course of disease on the prevalence was analyzed. Results: The oral fungal infection rate of erosive OLP patients was significantly higher than that of healthy volunteers. The infection rate of patients older than 45 years was significantly higher than that of patients 45 years old or less. The infection rate significantly increased in patients with duration longer than 6 months compared with that of patients with duration of 6 months or less. Conclusion: The incidence of oral fungal infection of patients with erosive OLP was higher, especially for the older patients with longer course of disease.