基于多组学水平的动物分子趋同演化研究新进展

Recent progress in convergent molecular evolution of animals based on multi-omics studies

表型趋同的分子证据探索一直是趋同演化研究的热点.高通量测序带来的多组学数据为分子趋同演化提供了大量研究材料和更加多样的研究角度.分子趋同的概念和研究方法也从编码基因的氨基酸替换趋同扩展到基因丢失趋同、表达调控趋同、表达模式趋同、肠道微生物趋同等多个不同分子层级.本文对近年来基因组时代下基于多组学水平的分子趋同演化研究的新进展进行综述,并对该领域未来研究方向进行了展望.

Molecular evidence for phenotypic convergence has been a hot topic in convergent evolution research. High-throughput sequencing techniques produce multi-omics data, providing a large number of research materials and more diverse perspectives for convergent molecular evolution. The concept of molecular convergence extends from the convergence of amino acid replacement coding genes to that of gene loss, expression regulation, expression patterns, and metagenomic convergence. Based on different concepts, materials, and purposes, the methods of molecular convergence are continually expanding and being updated. This paper reviews the recent progress in convergent molecular evolution of animals based on multi-omics studies in the genomic era. The future research directions in this field are also investigated.