婆罗双树样基因4在肺癌中的研究进展

Advances in research of Sal-like 4 in lung neoplasms

婆罗双树样基因4是一种具有锌指结构蛋白的转录因子,参与多种人类恶性肿瘤的发生与发展.肺癌目前是全球发病率、病死率双第一的恶性肿瘤疾病,总体预后水平欠佳,近来已有研究发现Sall4参与肺癌的发生与发展,本文从Sall4基因在肺癌的发生、发展中的作用等方面进行综述.

Sal-like 4 ( Sall4 ), which is a transcription factor with a zinc finger structure protein, is involved in the occurrence and development of various human malignant tumors. Lung cancer is a malignant tumor with highest morbidity and maximum mortality in the current, and its overall prognosis is poor. Recently, it has been found that Sall4 is involved in the occurrence and development of lung cancer, This article is reviewed from the above aspects.