摘要
阻塞性睡眠呼吸暂停低通气综合征(OSAHS)作为一种常见病,可导致呼吸系统在内的多系统病理生理改变,其与间歇性低氧(IH)关系密切。探讨IH对肺组织的损伤及机制对研究OSAHS对呼吸系统的病理生理影响有重大意义。本文就IH对肺组织的损伤及机制作一综述。
As a common disease, obstructive sleep apnea hypopnea syndrome (OSAS) may induce pathophysiological changes of multisystem including respiratory system which is closely related to intermittent hypoxia (IH). Discussing injury of IH to lung tissue and related mechanisms is of great significance to the research of pathophysiological effects of OSAS to respiratory system. This article made a review about injury of IH to lung tissue and related mechanisms.
作者
刘玉东
段争
Liu Yudong;Duan Zheng(The Second Departmerit of Respiratory Medicine, the Second Hospital of Hebei MedicalUniversity, Shijiazhuang 050000, China)
出处
《国际呼吸杂志》
2019年第14期1110-1112,共3页
International Journal of Respiration
基金
河北省重大科技成果转化专项项目(15277701D).
关键词
活性氧化物
氧化应激
线粒体损伤
间歇性低氧
炎症损伤
Reactive oxygen species
Oxidative stress
Mitochondrial damage
Intermittent hypoxia
Inflammatory injury
