汉防己甲素联合乙酰半胱氨酸泡腾片治疗矽肺临床效果评价探究

Clinical evaluation of tetrandrine combined with acetylcysteine effervescent tablets in the treatment of silicosis

目的:探究汉防己甲素联合乙酰半胱氨酸泡腾片治疗矽肺临床效果。方法:收治矽肺患者56例,分为两组各28例。对照组实施常规的药物治疗,试验组给予汉防己甲素联合乙酰半胱氨酸泡腾片进行治疗。对患者治疗前后肺通气功能的变化情况进行比较,同时记录观察两组患者的不良反应发生率。结果:治疗后两组肺通气功能得到有效改善,但试验组的改善程度更优,同时出现的不良反应较少,差异有统计学意义(P<0.05)。结论:汉防己甲素联合乙酰半胱氨酸泡腾片治疗矽肺的效果良好,可对其肺部功能有所改善,且不良反应发生率也较低。

Objective:To explore the clinical effect of tetrandrine combined with acetylcysteine effervescent tablets in the treatment of silicosis.Methods:56 silicosis patients were selected,they were divided into the two groups with 28 cases in each group.The control group was treated with routine drug therapy,while the experimental group was treated with tetrandrine combined with acetylcysteine effervescent tablets.According to the changes of pulmonary ventilation function before and after treatment,the incidence of adverse reactions in two groups was recorded and observed.Results:After treatment,the pulmonary ventilation function of the two groups was effectively improved,but the improvement degree of the experimental group was better,with fewer adverse reactions,the difference was statistically significant(P<0.05).Conclusion:Tetrandrine combined with acetylcysteine effervescent tablets has a good effect on the lung function,and the incidence of adverse reactions is also low.