中老年人腹部脂肪面积和分布与颈动脉粥样硬化进展的关系

Correlation of abdominal fat area and distribution with carotid atherosclerosis progress in middle aged and elderly people

目的探讨中老年人腹部脂肪面积和分布与颈动脉粥样硬化进展之间的关系。方法选取北京协和医院保健医疗部2015至2016年140例体检者,使用腹部CT计算其腹部脂肪面积与分布,根据颈动脉超声结果评估颈动脉粥样硬化程度变化,分析腹部脂面容积及分布的情况与颈动脉粥样硬化发展的相关性。结果51-100岁人群,颈动脉斑块增厚组与动脉硬化未进展组和斑块减轻组比较,腹部脂肪面积和分布差异均无统计学意义;在51-80岁人群中,颈动脉斑块增厚组与动脉硬化未进展组和斑块减轻组比较,腹部脂肪面容积均明显增大(P=0.05,P=0.03),腹部内脏脂肪面积虽有增大趋势,但差异无统计学意义(P均>0.05),腹部脂肪分布情况差异无统计学意义(P均〉0.05)。结论在51-80岁人群中,腹部脂肪总面积较小的人,更少出现颈动脉粥样硬化进展。

Objective To analyze the relationship between the abdominal fat and the progress of carotid atherosclerosis in the subject ageing 51-100 years. Methods 140 subjects receiving health examination in the department of health of Peking Union Medical College Hospital from 2015 to 2016 were included in the research. The abdominal fat area and distribution were calculated according to abdominal CT, and the progress of atherosclerosis in carotid artery was determined by ultrasound. Results In the population of 51 -100 years old, there were no statistically significant difference in abdominal fat area and distribution among carotid artery plaque thickening group, arteriosclerosis non-progressing group and plaque reducing group;In the population of 51-80 years old, the total abdominal fat was significantly higher in carotid artery plaque thickening group than in arteriosclerosis non-progressing group and plaque reducing group (P=0.05, P = 0.03), abdominal visceral fat area also increased ,but no significant difference was found (P>0.05), and no significant differences in abdominal fat distribution was found (P>0.05. Conclusion The less total area of abdominal fat is, the slower the progress of ather-osclerosis in carotid artery is in the population of 51-80 years old.