营养素感应系统与肠道微生态

Sensing of nutrients and intestinal microecology

营养素感应系统与肠道微生态对于维持机体生命活动是必需的,营养素感应分子作为关键因子调控一系列营养代谢相关的病理生理过程。肠道微生物感应分子对于肠道微生态和肠道内稳态的维持至关重要,但其中具体机制仍有待于进一步探索。本文就肠道营养素感应系统及肠道微生态相关分子调控机制进行综述。

Sensing of nutrients and intestinal microecology are necessary for life. The nutrient sensing molecules are key factors to regulate a series of pathophysiological processes in nutrition metabolism. Microbial sensing molecules in the gut play critical roles in intestinal microecology and maintenance of the gut homeostasis. However, the specific mechanism remains to be further explored. This article reviews the intestinal nutrient sensing system and the molecular regulation mechanism of the intestinal microelogy.