观察替格瑞洛用于老年急性ST段抬高型心肌梗死患者的治疗效果

Observe the Therapeutic Effect of Ticagrelor in Elderly Patients with Acute ST-segment Elevation Myocardial Infarction

目的分析替格瑞洛用于老年急性ST段抬高型心肌梗死患者的治疗效果。方法选取120例老年急性ST段抬高型心肌梗死患者随机分为对照组60例,观察组60例。对照组患者在基础治疗上口服氯吡格雷药物治疗,观察组在基础治疗上采用替格瑞洛药物治疗,观察两组患者治疗之后的心功能改善情况、心血管疾病的发生几率以及出血率。结果观察组心功能改善情况和心血管疾病的发生几率都明显优于对照组,组间数据检验结果有显著差异,P<0.05,有统计学意义;观察组出血率明显低于对照组,P<0.05。结论在治疗老年急性ST段抬高型心肌梗死中使用替格瑞洛药物治疗,可以有效地改善患者心功能的状态,降低心血管疾病的发生几率,降低出血的风险,值得临床上推广应用。

Objective To analyze the therapeutic effect of ticagrelor in elderly patients with acute ST-segment elevation myocardial infarction.Methods One hundred and twenty elderly patients with acute ST-segment elevation myocardial infarction were randomly divided into control group(60 cases)and observation group (60 cases).The patients in the control group were treated with oral clopidogrel in the basic treatment.The observation group was treated with ticagrelor in the basic treatment.The improvement of cardiac function,incidence of cardiovascular disease and bleeding rate after treatment were observed in both groups.Results The improvement of cardiac function and the incidence of cardiovascular disease in the observation group were significantly better than those in the control group.There was a significant difference in the data between the groups,P<0.05,which was statistically significant.The bleeding rate in the observation group was significantly lower than that in the control group (P<0.05).Conclusion The use of ticagrelor in the treatment of elderly patients with acute ST-segment elevation myocardial infarction can effectively improve the state of cardiac function and reduce the incidence of cardiovascular disease,reduce the risk of bleeding,which is worthy of clinical application.