探究慢性顽固性胃炎患者接受硫糖铝与黄连素治疗的临床价值

To Explore the Clinical Value of Sucralfate and Berberine in Patients with Chronic Refractory Gastritis

目的探讨慢性顽固性胃炎患者接受硫糖铝与黄连素治疗的临床价值。方法选取本院92例慢性顽固性胃炎患者为研究对象,用随机数字表法分为两组(n=46),对照组给予黄连素治疗,研究组给予硫糖铝与黄连素治疗,对比两组观察指标、不良反应及复发率、治疗效果。结果研究组治疗、病症消失、检查结果转阴时间均显著低于对照组(P<0.05)。研究组不良反应率23.9%明显低于对照组63.0%(P<0.05);研究组复发率4.3%显著低于对照组23.9%(P<0.05)。研究组治疗有效率93.5%显著高于对照组76.1%(P<0.05)。结论慢性顽固性胃炎患者接受硫糖铝与黄连素联合治疗,其不良反应及复发率减少,治疗有效率提高,值得临床上应用。

Objective To investigate the clinical value of sucralfate and berberine in the treatment of chronic refractory gastritis. Methods 92 patients with chronic refractory gastritis were selected as the research object. They were divided into two groups by random number table method(n=46). The control group was treated with berberine,and the group was treated with aluminum thiose and berberine, and the two groups were compared with each other.Results The study group was significantly lower than the control group(P<0.05). The adverse reaction rate of 23.9% in the study group was significantly lower than that of the control group of 63.0%(P< 0.05);The recurrence rate of 4.3%in the study group was significantly lower than that of the control group of 23.9%(P<0.05). The effective rate of 93.5%in the study group was significantly higher than that of the control group 76.1%(P<0.05).Conclusion After combined treatment of sucralfate and berberine, the adverse reactions and recurrence rate of chronic refractory gastritis patients are reduced, and the effective rate of treatment is improved, which is worthy of clinical application.