脑卒中高危人群筛查中同型半胱氨酸检测的应用研究

A Study on the Application of Homocysteine Detection in Screening of High-risk Population of Cerebral Stroke

目的探析脑卒中高危人群筛查中同型半胱氨酸检测的应用效果。方法此研究病例时间所取时段为2017年2月至2019年1月,对我院接收的脑卒中者36例和脑卒中高危者36例的临床资料进行回顾性分析,并将其分别设为甲组和乙组;同期另选取健康体检者36例作为对照组。比较被选对象的同型半胱氨酸和血脂、血压和血糖等指标水平。结果除高密度脂蛋白指标,健康组的血脂、血压和血糖水平情况均低于甲组和乙组;健康组同性别者同型半胱氨酸水平均明显低于甲组与乙组;组内女性别者同型半胱氨酸水平明显低于男性,差异有统计学意义(P<0.05)。结论在脑卒中高危人群筛查中,同型半胱氨酸检测的实施能取得较高的诊断检测价值。

Objective To investigate the effects of the application of homocysteine detection in screening of high-risk population of cerebral stroke.Methods Retrospective analysis was employed for study.The clinical data of 36 patients with cerebral stroke and 36 high-risk patients with cerebral stroke who were treated in Tianshan Road Community Health Service Center from February 2017 to January 2019 constituted group A and group B respectively. Another 36 people who received health examination during the same period comprised the control group.The levels of homocysteine,blood lipid,blood pressure and blood glucose were compared among the three groups.Results Except for the indexes of high-density lipoprotein,the levels of blood lipid,blood pressure and blood glucose of the people in control group were lower than those in group A and group B.The homocysteine level of the people in the control group was significantly lower than that of the patients of the same gender in group A and group B.The homocysteine level of females was significantly lower than that of males and the difference was statistically significant (P<0.05). Conclusion The application of homocysteine detection can achieve high value in diagnose and detection in screening of high-risk population of cerebral stroke.