摘要
病理性骨化是强直性脊柱炎最主要的特点之一。目前有很多关于强直性脊柱炎骨化的研究,包括炎症与骨化的关系、骨化信号通路及Wnt信号通路等。从不同的方面来研究强直性脊柱炎的骨化过程,彻底弄清其骨化的机制,对治疗强直性脊柱炎有着重要的意义。
Pathological ossification is one of the most important features of ankylosing spondylitis.There are many studies on the ossification of ankylosing spondylitis,including the relationship between inflammation and ossification,ossification signal pathway and Wnt signaling pathway.To study the ossification process of ankylosing spondylitis from different aspects and thoroughly understand the mechanism of ossification,it is of great significance for the treatment of ankylosing spondylitis.
作者
万文凯
徐一宏
徐卫东
Wan Wenkai;Xu Yihong;Xu Weidong(Department of Joint & Bone Surgery,Changhai Hospital,the First Affiliated Hospital of the Second Military Medical University,Shanghai 200433,China)
出处
《中华关节外科杂志（电子版）》
CAS
CSCD
2019年第3期348-352,共5页
Chinese Journal of Joint Surgery(Electronic Edition)
基金
国家自然科学基金(81672126,81871751)
关键词
骨生成
炎症
WNT信号通路
Osteogenesis
Inflammation
Wnt signaling pathway
