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足细胞自噬在IgA肾病中的研究进展 被引量:1

Reasearch progress of podocyte autophagy in IgA nephropathy
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摘要 IgA肾病是一种慢性肾小球疾病,以蛋白尿为主要临床表现,可导致肾功能的不可逆下降,最后进展至终末期肾功能衰竭.肾小球足细胞是高度分化的上皮细胞,在肾小球滤过过程中发挥重要作用.IgA肾病中肾小球基底膜足细胞丢失可能导致或促进蛋白尿的进展,足细胞损伤是肾小球疾病和终末期肾病的关键因素,而足细胞自噬对肾小球硬化和衰老相关的肾功能障碍具有保护作用.
作者 李楸莹(综述) 沈清(审校) Li Qiuying
出处 《国际泌尿系统杂志》 2019年第4期718-720,共3页 International Journal of Urology and Nephrology
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