乳果糖与小麦纤维素治疗妊娠期便秘的疗效对比观察

Lactulose and Wheat Cellulose in the Treatment of Gravidic Constipation:Effect Comparison

为探究乳果糖与小麦纤维素口服治疗妊娠期便秘的疗效。选取本院86例妊娠期便秘患者,随机分为乳果糖组和小麦纤维素组,各43例。乳果糖组采用乳果糖口服,小麦纤维素组口服小麦纤维素。观察2组疗效,便秘症状积分及不良反应情况。结果显示,2组患者疗效相当(P>0.05);治疗后2组便秘症状积分均有明显下降,在排便不尽感积分方面,小麦纤维素组下降更明显(P<0.05),在排便频率积分方面,乳果糖组积分降低更显著(P<0.05);2组患者不良反应发生率比较差异无统计学意义(P>0.05)。结果表明,乳果糖及小麦纤维素治疗妊娠期便秘疗效确切,临床应用中,应当依据患者具体病情选择药物开展治疗。

This study was to investigate effect of lactulose and wheat cellalose in the treatment of gravidic constipation,enrolled 86 cases of this constipation and randomly divided them into lactulose group(shortened to Lg,43 cases,oral administered lactulose)and wheat cellulose group(shortened to Wg,43 cases,wheat cellulose),then observed both groups’ effect,the score on constipation symptoms,and untoward reaction status.As results,both groups’ effect was same(P >0.05);after treatment the score on constipation symptoms in both groups was all declined significantly,and in the score on unended sensation for bowel movement Wg was more declined(P <0.05);in the score on defecation frequency,Lg was more declined(P <0.05);in the incidence rate of untoward reaction there was no statistical difference between Lg and Wg(P >0.05).Results show that both things all have certain effect in the treatment of gravidic constipation;hence clinically it should be selective medication according to patients’ relevant conditions.