非小细胞肺癌化疗患者应对方式与生活质量的相关性研究

Correlation between Coping Style and Quality of Life in Chemotherapy Patients with Non-small Cell Lung Cancer

目的:调查非小细胞肺癌(NSCLC)化疗患者应对方式与生活质量的相关性。方法:选择2016年5月-2018年5月在我院接受化疗的NSCLC患者共110例,分别采用肺癌生命质量量表(EORTC-QLQ.C30)、肺癌患者生活质量调查问卷(EORTC-QLQ.LC13)和医学应对方式问卷(MCMQ)对患者生活质量与应对方式进行调查,分析其相关性,并采用多元逐步回归分析整体生活质量的影响因素。结果:不同化疗阶段,患者功能维度得分和整体生活质量得分显著下降,差异有统计学意义(P<0.05),症状维度得分和化疗相关副反应得分显著升高,差异有统计学意义(P<0.05)。肺癌表现得分的差异和三种应对方式得分的差异均无统计学意义(P>0.05)。患者采取面对方式和回避方式的得分均高于屈服方式(P<0.05)。面对方式与患者整体生活质量呈正相关,回避方式、屈服方式与患者整体生活质量呈负相关。多元逐步回归分析显示:年龄、疾病转移及面对方式是NSCLC化疗患者整体生活质量的影响因素(P<0.05)。结论:NSCLC化疗患者应对方式与生活质量存在一定的相关性,应有效的发挥积极应对方式对生活质量的促进作用,提高患者生活质量。

Objective: To explore the correlation between coping style and quality of life in chemotherapy patients with non-small cell lung cancer(NSCLC). Methods: A total of 110 patients with NSCLC, who were treated in No.302 Hospital of China Guizhou Aviation Group from May 2016 to May 2018, were selected. The lung cancer life quality scale(EORTC-QLQ.C30), lung cancer patients’ quality of life questionnaire(EORTC-QLQ.LC13) and Medical Coping Style Questionnaire(MCMQ)were used to investigate the quality of life and coping style of the patients, the correlation was analyzed, and the influencing factors of overall quality of life were analyzed by multiple stepwise regression. Results: Functional dimension scores and whole quality of life scores of the patients decreased significantly during different chemotherapy phases, the differences were statistically significant(P<0.05). The scores of symptom dimension and side effects associated with chemotherapy increased significantly, the differences were statistically significant(P<0.05). The differences of lung cancer performance scores and three kinds of coping scores were not statistically significant(P>0.05). The scores of patients taking the facing style and the evasion style were higher than those of the yield style(P<0.05). The facing style and quality of life showed a positive correlation. The evasion style and the yield style showed a negative correlation with quality of life.Multiple stepwise regression analysis showed that age, disease metastasis and the way to face were the influencing factors of the overall quality of life chemotherapy patients with NSCLC. Conclusion: There is a certain correlation between the coping style and the quality of life in chemotherapy patients with NSCLC. The positive coping style of patients should be advocated to improve their quality of life.