药师干预在围术期预防应用抗菌药物中的效果分析

Effect analysis of pharmacist intervention in perioperative prophylactic application of antibiotics

目的探讨药师干预在围术期预防应用抗菌药物中的效果。方法选取2017年8月至2018年8月在浙江省荣军医院接受手术治疗的患者148例,采用奇偶分组法分为两组,对照组74例患者在使用抗菌药物时,未经过药师干预;观察组74例患者在使用抗菌药物时经过药师干预。对比两组患者抗菌药物的使用情况。结果观察组预防用药时间为(2.59±0.24)d、住院时间为(8.47±0.83)d,对照组预防用药时间、住院时间分别为(3.76±0.36)d、(10.74±1.32)d,两组差异均有统计学意义(t=23.262、12.523,均P<0.01);观察组抗菌药物总费用为(778.62±76.35)元、总药品费用为(3 036.75±302.11)元,对照组分别为(1 063.26±105.32)元、(4 698.64±1 452.28)元,两组差异均有统计学意义(t=18.823、9.638,均P<0.01);观察组患者对抗菌药物使用的满意度为97.30%(72/74),对照组为74.32%(55/74),两组差异有统计学意义(χ^2=16.038,P<0.01)。结论对围术期预防应用抗菌药物的患者实施药师干预,可以促使抗菌药物的合理使用。

Objective To investigate the efficacy of pharmacist intervention in perioperative prophylactic application of antibiotics. Methods From August 2017 to August 2018, 148 cases received surgery in Zhejiang Rongjun Hospital were selected, using odd-even grouping method, the patients were divided into two groups, with 74 cases in each group.The control group used antibacterial drugs without pharmacists intervention, the observation group used antibacterial drugs through pharmacists intervention.The use of antimicrobial agents was compared between the two groups. Results The duration of prophylactic medication, the duration of hospitalization in the observation group were (2.59±0.24)d,(8.47±0.83)d, respectively, which in the control group were (3.76±0.36)d,(10.74±1.32)d, respectively, the differences between the two groups were statistically significant(t=23.262, 12.523, all P<0.01). The total cost of antibacterial drugs and the total drug cost in the observation group were (778.62±76.35)CNY,(3 036.75±302.11)CNY, respectively, which in the control group were (1 063.26±105.32)CNY,(4 698.64±1 452.28)CNY, respectively, and the differences between the two groups were statistically significant(t=18.823, 9.638, all P<0.01). The antibacterial drug use satisfaction of the observation group was 97.30%(72/74), which of the control group was 74.32%(55/74), the difference between the two groups was statistically significant(χ^2=16.038, P<0.01). Conclusion The rational use of antibiotics can be promoted by pharmacist intervention in perioperative prophylaxis patients.