氨氯地平治疗高血压的应用进展

Progress in the application of amlodipine in the treatment of hypertension

高血压是一种以体循环动脉血压增高为主要特征的慢性疾病,可并发一系列心脑血管或肾脏等器官损害。目前的临床治疗中往往不能直接对其进行根治,需要使用药物以及生活习惯纠正等方式对患者进行血压控制。在这种情况下,选择具有明显降压效果的优质降压药物为患者提供治疗十分关键,另外高血压疾病的治疗与控制是一个相对较慢的过程,不少患者需要比较长的疗程帮助纠正其异常的血压,因此关于降压药物的毒性、副作用等情况也需要被考虑在内。现阶段应用较广的降压药物包括利尿剂、β受体阻滞剂、钙通道阻滞剂、血管紧张素转换酶抑制剂等药物,氨氯地平作为钙通道阻滞剂对高血压疾病具有良好的控制作用,临床应用比较广泛。

Hypertension is a chronic disease characterized by elevated blood pressure in systemic and circulatory arteries, complicated by a series of cardiovascular, cerebrovascular or renal organ damage.The current clinical treatment often can not be directly cured,which need to use drugs and life habits to correct the way to control blood pressure in patients.In this case, it is very important to choose high-quality antihypertensive drugs with significant antihypertensive effect to provide treatment for patients.In addition,the treatment and control of hypertension is a relatively slow process.Many patients need a longer course of treatment to help correct their abnormal blood pressure.Therefore,the toxicity and side effects of antihypertensive drugs need to be taken into account.At present,widely used antihypertensive drugs include diuretics, beta-blockers, calcium channel blockers, angiotensin-converting enzyme inhibitors and other drugs.Amlodipine, as a calcium channel blocker,has a good control effect on hypertension,and its clinical application is more extensive.