摘要
经典骨髓增殖性肿瘤(MPN)遗传学特征已经在很大程度上被阐明.文章旨在对MPN基因突变谱的研究进展作一综述,帮助临床更好地对此类患者进行分层,制定个性化的治疗策略从而实现精准医疗.
The genetic characteristics of classical myeloproliferative neoplasms(MPN)have been largely elucidated.This article aims to review the research progress of MPN mutation spectrum.Therefore,patients can be better stratified and personalized treatment strategies will be achieved.
作者
任颜
许晶
陈秀花
王宏伟
Ren Yan;Xu Jing;Chen Xiuhua;Wang Hongwei(Shanxi Provincial Key Laboratory of Molecular Diagnosis and Treatment of Blood Diseases, Institute of Blood Diseases, the Second Hospital of Shanxi Medical University, the Second Clinical Medical College of Shanxi Medical University, Taiyuan 030001, China)
出处
《白血病．淋巴瘤》
CAS
2019年第7期437-441,共5页
Journal of Leukemia & Lymphoma
基金
国家自然科学基金(81670126).
关键词
骨髓增殖性肿瘤
基因
突变
Myeloproliferative neoplasms
Genes
Mutation
