高渗盐水联合吡拉西坦对老年重症脑出血的治疗作用

Therapeutic Effects of Hypertonic Saline Combined with Piracetam on Severe Cerebral Hemorrhage in Older Patients

目的探讨高渗盐水联合吡拉西坦对老年重症脑出血的治疗作用。方法选取2016年3月~2018年2月我院收治的老年重症脑出血患者98例,采用数字化列表随机分为对照组和观察组。对照组给予吡拉西坦静脉滴注,观察组给予高渗盐水联合吡拉西坦静脉滴注,比较两组治疗前后颅内压变化、神经功能缺损评分(NIHSS)、临床疗效及不良反应的发生情况。结果治疗后,观察组颅内压及NIHSS明显低于对照组(P<0.05);临床总有效率明显高于对照组;不良反应发生率明显低于对照组(P<0.05)。结论高渗盐水联合吡拉西坦可降低老年重症脑出血患者的颅内压,改善患者神经功能缺损,值得临床上推广使用。

Objective To explore the therapeutic effects of hypertonic saline combined with piracetam on severe cerebral hemorrhage in older patients. Methods 98 older patients with severe cerebral hemorrhage in our hospital between March 2016 and February 2018 were randomly divided into the control group and the observation group. The control group was given piracetam intravenously. The observation group was given hypertonic saline combined with piracetam. The intracranial pressure, NIH stroke scale (NIHSS) and adverse reactions in the two groups were recorded. Results After treatment, the intracranial pressure and NIHSS in the observation group were significantly lower than those in the control group ( P < 0. 05). The overall response rate in the observation group was significantly higher than that in the control group ( P < 0. 05). The incidence of adverse reactions in the observation group were significantly lower than that in the control group (P < 0. 05). Conclusion Hypertonic saline combined with piracetam reduces intracranial pressure and improves the neurological deficits in older patients with severe cerebral hemorrhage.