静脉预注右美托咪定对无抽搐电休克治疗患者麻醉恢复质量的影响

Effect of dexmedetomidine pre-injection on the quality of anesthesia recovery in patients undergoing convulsion-free electroconvulsive therapy

目的观察静脉预注右美托咪定对无抽搐电休克治疗患者麻醉恢复质量的影响。方法 100例行无抽搐电休克治疗的患者随机均分为右美托咪定组(D组)和对照组(C组)。D组麻醉前10 min静脉泵注右美托咪定0.4μg/kg,C组静脉泵注等容量生理盐水。两组患者均采用静脉注射丙泊酚和琥珀胆碱麻醉。记录两组患者抽搐时间、苏醒时间、术后0.5 h(T1)、1 h(T2)和5 h(T3)的VAS疼痛评分、麻醉恢复期躁动评分和不良反应的发生情况。结果两组患者抽搐时间和苏醒时间无统计学差异(P>0.05)。与C组相比,D组患者T1~T3时的VAS疼痛评分、麻醉恢复期躁动评分和不良反应发生率均较低(P<0.05)。结论静脉预注右美托咪定能提高无抽搐电休克治疗患者的麻醉恢复质量。

Objective To observe the effect of dexmedetomidine pre-injection on the quality of anesthesia recovery in the patients undergoing convulsion-free electroconvulsive therapy.Methods A total of 100 patients undergoing convulsion-free electroconvulsive therapy was equally randomized into two groups.Group D received dexmedetomidine 0.4 μg/kg intravenously infused in 10 minutes before anesthesia and group C received same volume of normal saline as the control.All patients received intravenous anesthesia with propofol and succinylcholine. The seizure duration,recovery time,VAS pain scores at 30 minutes(T1),1 hour(T2) and 5 hours(T3) after operation,the agitation scores and adverse responses during recovery period of anesthesia were recorded.Results There was no significant difference in the times of seizure and recovery between two groups(P>0.05).Compared with group C,the VAS pain scores at T1 to T3,the agitation scores and the incidence of adverse responses during recovery period in group D were decreased(P<0.05).ConclusionDexmedetomidine pre-injection can significantly improve the quality of anesthesia recovery in the patients undergoing convulsion-free electroconvulsive therapy.