四维锥形束CT在肺癌放疗中的应用

The application of four-dimensional cone-beam CT in radiotherapy for lung cancer

放疗是治疗肺癌的重要手段,但肺癌的运动给精确放疗的实施带来挑战。四维锥形束CT是一种四维影像技术,能够提供肿瘤的时空位置信息,从而提高肺癌放疗的精度。本文回顾分析了肺癌四维锥形束CT在测量和修正摆位误差、观察肿瘤位置及运动变化、指导靶区勾画及外放、剂量计算等领域的研究现状和发展趋势。

Radiotherapy is an indispensable treatment of lung cancer. However, movement of lung cancer brings challenges to precise radiotherapy. Four-dimensional cone-beam CT is a four-dimensional imaging technique, which can demonstrate the tumor trajectory to improve the accuracy of radiotherapy. In this article, the research status and development tendency of four-dimentional cone-beam CT in terms of measuring and correcting set-up errors, observing variability of tumor postion and movement, guiding delineation of target volumes as well as calculating radiation dose were retrospectively reviewed.