中药对细菌生物被膜作用机制的研究进展

Research progress on mechanism of traditional Chinese medicine on bacterial biofilm

如今越来越多耐药细菌的出现,对于细菌耐药的研究显得更为迫切,而现今的研究已经发现细菌的生物被膜是其耐药作用的一个独特机制。许多中药被发现对于细菌的生物被膜具有抑制作用,是细菌耐药性研究中一个独特的研究领域。通过查阅分析国内外有关中药对细菌生物被膜抗菌作用的文献,从细菌生物被膜形成过程、细菌生物被膜的耐药机制以及中药对于细菌生物被膜的作用等方面进行综述,为进一步研究中药的抗菌作用提供参考。

With the emergence of more and more drug-resistant bacteria, the research on bacterial resistance is much more urgent, and many researchers have found that the biofilm of bacteria is a unique mechanism of its drug resistance. Many traditional Chinese medicine have been found to inhibit the biofilm of bacteria and provoked unique research field in bacterial resistance. By consulting and analyzing the local and international researches on the antibacterial effect of traditional Chinese medicine on bacterial biofilms,from aspects of bacterial biofilm formation process, biofilm resistance mechanism as well as how traditional Chinese medicine affecting biofilms, to provide references for further researches on antibacterial action of traditional Chinese medicine.