肺癌的胸外科临床试验研究现状

Current status of clinical trials about thoracic surgery in lung cancer

我国肺癌发病率在男性和女性中分别高居首位和第2位;同时,肺癌也是我国恶性肿瘤的首要死因。外科治疗对改善肺癌患者预后具有重要意义,相关临床试验数量在逐年增加。通过对Clinicaltrials.gov平台上在研的肺癌胸外科领域临床试验进行回顾性总结,本文发现相关临床试验主要关注于治疗、围手术期管理及基础研究。我国的临床试验虽然起步晚,但是发展迅速,临床试验数目位列第2。此外,我国的临床试验在试验设计和研究范围等方面存在一些不足,与国外研究仍有一定差距。

The incidence of lung cancer in China ranks first and second among men and women respectively. Meanwhile, lung cancer is also the leading cause of death in malignant tumors in China. Surgical treatment is of great significance in improving the prognosis of patients with lung cancer, and the number of related clinical trials is increasing year by year. Through a retrospective review of clinical trials in the field of lung cancer and thoracic surgery on the Clinicaltrials.gov platform, this article finds that relevant clinical trials focus on treatment, perioperative management and basic research. Although the clinical trials in China started late, they have developed rapidly and the number of clinical trials ranked second. In addition, there are some shortcomings in the clinical trials of China in terms of trial design and research scope, and there is still a gap between Chinese and foreign trials.