安徽省界首市2014-2018年围产儿出生缺陷监测结果分析

Analysis of monitoring results of perinatal birth defects in Jieshou city from 2014 to 2018

目的分析界首市出生缺陷发生现状及变化趋势,探讨减少本地区出生缺陷发生的有效干预措施。方法对2014-2018年5年内界首市两家国家级出生缺陷医院监测项目点住院分娩的孕28周至产后7天内的围产儿报表资料进行分析。结果共监测围产儿39 124人。报告出生缺陷357例,围产儿出生缺陷发生率为9.12‰,围产儿出生缺陷发生率前五位为多(并)指(趾)、外耳畸形、先天性心脏病、唇腭裂、脑部畸形(包括脑积水、脑膨出及无脑)。男性围产儿、孕母年龄≤20岁或≥35岁的围产儿出生缺陷发生率较高。结论界首市围产儿出生缺陷发生率呈逐年上升趋势,应切实推进三级预防,降低围产儿出生缺陷发生率。

Objective To analyze the current situation and trend of birth defects in Jieshou City,and to explore effective intervention measures to reduce the occurrence of birth defects in this area. Methods The data of perinatal reports from 28 weeks of gestation to 7 days of postpartum delivery in two monitoring project sites of national birth defect hospitals in Jieshou City from 2014 to2018 were analyzed. Results A total of 39 124 perinatal infants were monitored. 357 cases of birth defects were reported. The incidence of perinatal birth defects was 9. 12 per thousand,showing an upward trend year by year( P < 0. 05). The top five perinatal birth defects were finger( toe),external ear deformity,congenital heart disease,cleft lip and palate,and brain deformity( including hydrocephalus,encephalocele and anencephalus). The incidence of birth defects was higher in male perinatal infants and pregnant women aged less than or equal to 20 years old or more than or equal to 35 years old. Conclusion The incidence of perinatal birth defects in Jieshou City is increasing year by year. Three-level prevention should be promoted to reduce the incidence of perinatal birth defects.