54549例住院患者梅毒血清学检测结果分析

Analysis of syphilis serological detection results in 54549 inpatients

目的:了解我院2017年住院患者梅毒血清学检测情况。方法:采用酶联免疫吸附法(ELISA-TP)筛查,筛查阳性者用甲苯胺红不加热试验(TRUST)试验和梅毒螺旋体明胶颗粒凝集试验(TPPA)检测。结果:共收集患者54549例,ELISA-TP阳性者1625例(检出率为3.00%),其中1145例再用TRUST和TPPA方法检测,双阳性172例,检出率为0.32%。结论:我院住院患者梅毒感染率高,应对入院患者进行梅毒常规筛查。

Objective:To investigate the syphilis serological detection among the inpatients in our hospital in 2017.Methods:Inpatients were tested by enzyme-linked immunosorbent assay-treponema pallidum(ELISA-TP).Then the positive samples of ELISA-TP were tested by tolulized red unheated serum test(TRUST)and treponema pallidum particle agglutination assay(TPPA).Results:Out of the 54 945 patients tested,ELISA-TP test was positive in 1625 patients.Of the 1625 positive patients,1145 were retested by TRUST and TPPA,of which both tests were positive in 172 samples,giving a positivity rate of 0.32%(172/54549).The 172 syphilis patients were distributed in 32 clinical departments.Some of them had no clinical symptoms,Conclusion:Since the infection rate of syphilis among the inpatients in our hospital is high,routine screening program for syphilis is recommended.