银屑病患者中甲真菌病患病率的病例对照研究

Comparative study on onychomycosis and fungal stains between the psoriatics and non-psoriatics

目的:比较银屑病患者与非银屑病患者甲真菌病患病率及感染菌种的差异。方法:收集2016年12月1日至2018年4月2日就诊于南京军区总医院皮肤科门诊的银屑病患者和非银屑病患者的临床资料,对外观异常甲行真菌镜检和真菌培养并进行菌种鉴定。真菌镜检和真菌培养均阳性者判定为阳性。结果:共收集银屑病患者198例和非银屑病患者对照168例,阳性率分别为11.1%和9.5%,差异无统计学意义(P=0.643)。银屑病患者病甲中培养出皮肤癣菌18例(81.8%),酵母菌4例(18.2%),非银屑病患者病甲中培养出皮肤癣菌15例(93.7%),酵母菌1例(6.3%),两组菌种差异无统计学意义(P=0.374)。结论:银屑病患者甲真菌病患病率及感染菌种与非银屑病患者无明显差异。

Objective:To compare the differences in onychomycosis and the fungal stains between the psoriatics and non-psoriatics.Methods:Psoriatic patients and non-psoriatic patients were collected from December 2016 to April 2018.Direct microscopic examination with 20%KOH and culture were carried out in abnormal nails in all patients and both positivity of the two methods was regarded as the positive standard.Results:One hundred and ninety eight psoriatic patients and 168 non-psoriatic patients were collected.The positivity rates in psoriatic patients and non-psoriatic patients were 11.1%and 9.5%,with no significance difference(P=0.643).Fungal stains identification showed that dermatophytes accounted for 81.8%and yeasts accounted for 18.2%in psoriatic patients,while dermatophytes accounted for 93.7%and yeasts accounted for 6.3%in non-psoriatic patients,with no significant differences(P>0.05).Conclusion:There is no significant difference in onychomycosis and fungal stains between the psoriatic patients and non-psoriatic patients.