老年痴呆患者院内感染的危险因素分析

Analysis of nosocomial infection in senile dementia patients

目的 对老年痴呆患者发生院内感染的危险因素进行分析,依据其危险因素制定相应的应对措施。方法 回顾性分析2015-03—2016-03驻马店市中心医院收治的老年痴呆患者68例,按照是否发生院内感染分为实验组(感染)和对照组(未感染),通过对比2组患者的临床资料,分析发生院内感染的影响因素。结果 发生院内感染的34例老年痴呆患者中以下呼吸道感染(38.2%)最多,其次为泌尿道感染(26.5%)、上呼吸道感染(17.7%)。通过对比2组患者的临床资料发现,性别、病程等与院内感染的发生率无相关性,而年龄、住院时间、抗生素使用、侵袭性操作、免疫抑制剂及激素的使用均为老年痴呆患者并发院内感染的危险因素。结论 住院时间、年龄、抗生素使用、侵袭性操作、免疫抑制剂及激素的使用均是导致老年痴呆患者发生院内感染的主要因素,对危险因素进行相应的预防措施以降低其院内感染的发生概率。

Objective To analyze the risk factors of nosocomial infection in senile dementia patients,and the corresponding countermeasures according to those risk factors. Methods We enrolled and analyzed 68 patients with senile dementia in our hospital from March 2015 to March 2016.We divided 34 patients with nosocomial infection as the experimental group and 34 other patients without nosocomial infection as the control group according to whether nosocomial infection occurred.We analyzed the clinical data of the two groups and compared with the influencing risk factors of nosocomial infection. Results Among 34 cases of senile dementia,lower respiratory infection (38.2%) was the main cause of nosocomial infection,followed by urinary infection (26.5%) and upper respiratory infection (17.7%).By comparing the clinical data of the two groups,there was no correlation between the incidence of nosocomial infection and gender,course of disease.Age,the hospitalization time,antibiotic therapeutic time,invasive operation,immunosuppressive agents and hormone use were the risk factors for nosocomial infection in senile dementia patients ( P <0.05). Conclusion The hospitalization time,age,antibiotic therapeutic time,invasive operation,immunosuppressive agents and hormone use are the main risk factors which cause nosocomial infection in senile dementia patients.According to those risk factors,we should carry out the preventive measures to reduce the incidence of nosocomial infection.