卵泡输出率的应用研究

Applied Research on Output Rate of Follicle

目前卵巢反应性的预测指标包括AMH、抑制素B、年龄、窦卵泡、基础性激素、卵巢敏感性(OSI)、卵泡敏感性(FSI)等,而这些指标在预测卵巢对外源性促性腺激素(Gn)的反应存在一定的局限性。在近年生殖医学预测IVF/ICSI妊娠结局及卵巢反应性的相关研究中,提出卵泡输出率(FORT)是一个客观、较新且热门的指标。控制性超促排卵(COH)个体化治疗方案的制定在治疗各种不孕症的过程中具有重要的意义,可以通过FORT评估每个患者卵巢反应性来制定合适的COH方案,从而改善妊娠结局。本文就FORT在卵巢低反应、多囊卵巢综合征(PCOS)、子宫内膜异位症(EMs)、不明原因不孕症、高龄及肿瘤患者对卵巢反应性及IVF/ICSI妊娠结局的相关性研究进行综述。

Current predictors of ovarian response include AMH,inhibin B,age,antral follicles,basal hormones,ovarian sensitivity(OSI),follicular sensitivity(FSI),etc.These indicators have certain limitations in predicting the response of ovarian to exogenous gonadotropin(Gn).In recent years,reproductive medicine predicts IVF/ICSI pregnancy outcomes and ovarian response studies;it is proposed that follicle output rate(FORT)is an objective,relatively new and popular indicator.The development of controlled ovarian hyperstimulation(COH)individualized treatment programs are of great significance in the treatment of various infertility.It can be used to determine the ovarian response of each patient by FORT to develop a suitable COH program to improve pregnancy outcomes..This article relates to the relationship between FORT in ovarian hyporesponsiveness,polycystic ovary syndrome(PCOS),endometriosis(EMs),unexplained infertility,advanced age and tumor patients with ovarian response and IVF/ICSI pregnancy outcomes.The study was reviewed.