初诊青年2型糖尿病临床特点及危险因素分析

Analysis of Clinical Features and Risk Factors of Type 2 Diabetes in Newly Diagnosed Youth

目的明确青年初诊2型糖尿病的临床特点并探讨相关危险因素,为预防高危因素青年人发生2型糖尿病提供理论依据。方法选择我院内分泌科2017年1月~2018年3月住院的313例初诊2型糖尿病患者,以40岁为界将其分为青年组及非青年组,分析患者的临床特点及危险因素。结果青年组男性构成率为75.76%,非青年组男性构成率为55.87%,两组性别构成率比较,差异有统计学意义(P<0.05);青年组收缩压(128.88±17.97)mmHg低于非青年组(137.47±19.44)mmHg,差异有统计学意义(P<0.05);青年组体重指数(26.02±4.80)kg/m2高于非青年组(24.52±3.41)kg/m2,差异具有统计学意义(P<0.05);青年组甘油三酯(3.62±3.44)mmol/L高于非青年组(2.87±3.35)mmol/L,差异有统计学意义(P<0.05);青年组高密度脂蛋白(1.03±0.35)mmol/L低于非青年组(1.14±0.37)mmol/L,差异有统计学意义(P<0.05)。初诊2型糖尿病为青年人的危险因素为性别(OR=2.07,95%CI:1.09~3.93,P<0.05)、BMI(OR=2.10,95%CI:1.14~3.18,P<0.05)及HDL-C(OR=1.98,95%CI:1.11~3.52,P<0.05)。结论男性、超重及肥胖、低高密度脂蛋白是青年人发生2型糖尿病的危险因素。

Objective To determine the clinical characteristics of newly diagnosed type 2 diabetes in young people and to explore related risk factors,so as to provide a theoretical basis for prevention of type 2 diabetes in young people with high risk factors.Methods 313 patients with newly diagnosed type 2 diabetes who were hospitalized from January 2017 to March 2018 in our hospital were divided into young and non-youth groups by age 40,and the clinical characteristics and risk factors were analyzed.Results The male composition rate was 75.76%in the youth group and 55.87%in the non-youth group.The gender composition rate was statistically significant(P<0.05).The young group systolic blood pressure(128.88±17.97)mmHg lower than the non-youth group(137.47±19.44)mmHg,the difference was statistically significant(P<0.05);the body mass index(26.02±4.80)kg/m2 in the young group was higher than that in the non-youth group(24.52±3.41)kg/m2,the difference was statistically significant(P<0.05);Triglyceride(3.62±3.44)mmol/L was higher than non-youth group(2.87±3.35)mmol/L,the difference was statistically significant(P<0.05);high density lipoprotein(1.03±0.35)mmol/L lower than the non-youth group(1.14±0.37)mmol/L,the difference was statistically significant(P<0.05).The risk factors for newly diagnosed type 2 diabetes were younger(OR=2.07,95%CI:1.09~3.93,P<0.05),BMI(OR=2.10,95%CI:1.14~3.18,P<0.05)and HDL-C(OR=1.98,95%CI:1.11 to 3.52,P<0.05).Conclusion Male,overweight and obese,low-density lipoprotein is risk factor for developing type 2 diabetes in young adults.