桑杏汤联合阿奇霉素治疗小儿肺炎支原体肺炎的临床疗效研究

The clinical efficacy of the Sangxing decoction plus azithromycin on children with mycoplasma pneumoniae pneumonia

目的:研究桑杏汤联合阿奇霉素治疗小儿肺炎支原体肺炎的临床疗效。方法:从本院2016年6月-2018年6月治疗的小儿肺炎支原体肺炎患儿中,抽取89例,随机分为两组,其中对照组45例、观察组44例。对照组应用阿奇霉素干混悬剂治疗,观察组在此基础上加用桑杏汤治疗,观察两组患儿临床治疗效果、症状和体征消失时间、不良反应发生率、证候积分、肺功能、血清炎性因子检查结果。结果:①观察组患儿临床治疗效果显著优于对照组;②症状、体征消失时间均显著短于对照组;③不良反应发生情况以及血清中炎性因子检测结果均显著低于对照组;④咳嗽、呕吐、发热、头痛等症状积分均显著低于对照组;⑤肺功能测定结果均显著优于对照组(P <0.05)。结论:应用桑杏汤联合阿奇霉素治疗小儿肺炎支原体肺炎疗效显著,能够有效缩短患儿发热时间、咳嗽时间,降低了患儿咳嗽、恶心、发热、头痛等证候积分、血清中的炎性因子和不良反应的发生率,以及有效改善了患儿的肺功能以及肺部啰音等情况,是理想的治疗方案。

Objective: To study the clinical efficacy of the Sangxing decoction (桑杏汤) plus azithromycin on children with mycoplasma pneumoniae pneumonia. Methods: 89 cases were randomly divided into the control group and the observation group. The control group was treated with azithromycin dry suspension. The observation group was treated with the Sangxing decoction more. The clinical effect, symptoms and signs disappear time, adverse reaction rate, symptom score, lung function, serum inflammatory factors were observed. Results: The efficiency in the observation group was significantly better than the control group. The symptoms and signs disappear time was significantly shorter than the control group. The adverse reactions and the serum inflammatory factors were significantly lower than the control group. The cough, vomiting, fever, headache and other symptoms were significantly lower than the control group.The lung function were significantly better than the control group(P<0.05). Conclusion: The Sangxing decoction plus azithromycin is effective on children with mycoplasma pneumoniae pneumonia, can effectively shorten the child’s fever and cough time, reduce the symptoms of cough, nausea, fever, headache, etc., the incidence of serum inflammatory factors and adverse reactions, effectively improve the lung function and lung noise.