当归饮子及血液灌流对血液透析患者皮肤瘙痒症的临床研究

A clinical study on treating pruritus in hemodialysis patients with Danggui Yinzi plus blood perfusion

目的:观察中药方当归饮子加减方及血液灌流对血液透析患者皮肤瘙痒症的临床疗效。方法:将30例符合研究要求的患者随机分为中药组和血液灌流组各15例。中药组行常规血液透析(HD),每周3次及当归饮子加减方汤剂每日1次;灌流组行常规血液透析治疗,每周2次,血液透析+血液灌流治疗每周1次。两组疗程均为4周。分别于治疗前及治疗4周后,调查两组患者的瘙痒评分指数,测定血肌酐、同型半胱氨酸(Hcy)、甲状旁腺激素(PTH)、β2-微球蛋白、血磷的水平。结果:中药组治疗的总有效率为73.33%,血液灌流组的总有效率为80.00%,中药组和血液灌流组对比,差异无统计学意义(P>0.05)。结论:当归饮子加减方及血液灌流对血液透析患者皮肤瘙痒症的治疗具有较好的临床疗效。

Objective: To observe the clinical effect of Danggui Yinzi (当归饮子) and blood perfusion on cutaneous pruritus in hemodialysis patients. Methods: 30 patients who met the research requirements were randomly divided into the TCM medicine group and the blood perfusion group. The TCM medicine group was given routine hemodialysis, 3 times a week, and Danggui Yinzi, once daily. The blood perfusion group was given routine hemodialysis, 2 times a week, hemodialysis plus blood perfusion, 1 time per week. Both groups were treated for 4 weeks. Results: The total effective rate in the TCM medicine group was 73.33%, and 80.00% in the blood perfusion group(P>0.05). Conclusion: Danggui Yinzi and blood perfusion have a good clinical effect on pruritus in hemodialysis patients.