黄连温胆汤治疗痰热内扰型失眠的效果观察

Observation on treating insomnia of Tanre Neirao type with the Huanglian Wendan decoction

目的:探讨黄连温胆汤治疗痰热内扰型失眠的效果。方法:选取我院2016年8月-2018年7月期间收治的72例痰热内扰型失眠患者,随机分为对照组和观察组,各36例。对照组采用常规西药治疗,观察组在对照组基础上增加黄连温胆汤治疗,对比两组治疗前后匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index,PSQI)变化,并对比两组临床疗效及不良反应情况。结果:观察组治疗2周后(9.56±1.67)分、4周后PSQI评分(5.69±1.57)分均显著低于对照组(9.36±1.69)分,差异具有统计学意义(P<0.05)。观察组总有效率(94.44%)显著高于对照组(77.78%),差异具有统计学意义(P<0.05)。观察组不良反应发生率(16.67%)与对照组(11.11%)比较,无显著差异(P>0.05),无统计学意义。结论:痰热内扰型失眠患者应用黄连温胆汤治疗,可有效改善失眠症状,并提高预后效果,临床应用安全有效。

Objective: To investigate the effect of the Huanglian Wendan decoction (黄连温胆汤) on insomnia of the Tanre Nierao type (痰热内扰型). Methods: 72 patients were randomly divided into the control group and observation group, 36 cases in each. The control group was treated with conventional western medicine, and the observation group was treated with the Huanglian Wendan decoction more. Results: PSQI was(9.56±1.67) in 2 weeks, and(5.69±1.57) in 4 weeks in the observation group, and were lower than(12.95±1.98,9.36±1.69) in the control group(P<0.05). The total efficiency in the observation group(94.44%) was significantly higher than 77.78%in the control group(P<0.05). There was no significant difference in adverse reactions between two groups(P>0.05). Conclusion: The Huanglian Wendan decoction on insomnia can effectively improve the symptoms of insomnia and the prognosis, with safety and efficiency.