中药饮片经不同炮制方法后的临床疗效分析

Clinical analysis of efficacy of TCM medicine by different processing methods

目的:对中药饮片经不同炮制方法后的临床疗效进行分析。方法:将2017年1月-2018年1月期间广东省韶关市中医院收治脾肺气虚型溃疡性结肠炎且使用参苓白术散进行治疗的120例患者作为此次研究对象,以随机分组的形式将其分为三组,分别为Ⅰ组、Ⅱ组与Ⅲ组,Ⅰ组40例为土炒白术,Ⅱ组40例为炙白术,Ⅲ组40例为焦白术,对其治疗效果进行分析对比。结果:①Ⅰ组患者治疗总有效率96.7%高于Ⅱ组治疗总有效率73.3%与Ⅲ组治疗总有效率76.7%,组间比较数据差异显著(P<0.05);Ⅱ组患者治疗总有效率73.3%与Ⅲ组治疗总有效率76.7%比较并无差异(P>0.05)。②Ⅰ组患者不良反应发生率13.2%低于Ⅱ组患者不良反应发生率36.7%与Ⅲ组患者不良反应发生率40.0%,组间比较数据差异显著(P<0.05);Ⅱ组患者不良反应发生率36.7%与Ⅲ组患者不良反应发生率40.0%比较并无差异(P>0.05)。结论:中药炮制技术是中医独有的优势,在对中药饮片进行炮制之前,应根据患者病症进行分型,根据分型结果选取相应的饮片炮制方法,以提高治疗的效果并保证治疗的安全性。

Objective: To analyze efficacy of TCM medicine by different processing methods. Methods: 120 cases of ulcerative colitis of the Pifei Qixu type (脾肺气虚型) were divided into 3 groups, 40 cases in each. All patients were given Shenling Baizhu San (参苓白术散). The group Ⅰ was given stir-baked Baizhu (白术) with soil;the group Ⅱ was given Zhi Baizhu (炙白术);the group Ⅲ was given Jiao Baizhu (焦白术). Results: The total efficiency in the group Ⅰ was 96.7%, which was higher than 73.3% in group Ⅱ and 76.7% in group Ⅲ(P<0.05). The total efficiency was 73.3% in group Ⅱ, and 76.7% in group Ⅲ(P>0.05). The incidence of adverse reactions in group Ⅰ was 13.2%, was lower than 36.7% in group Ⅱ and 40.0% in group Ⅲ(P<0.05). The incidence of adverse reactions in group Ⅱ was 36.7%, and 40.0% in group Ⅲ(P>0.05). Conclusion: TCM medicine processing technology is a unique advantage of Chinese medicine. Chinese medicine processing method according to the syndrome differentiation of the disease can improve the efficacy and safety.