探讨加味逍遥散治疗肝郁脾虚型功能性消化不良的效果

To Explore the Effect of Jiawei Xiaoyao Powder on Functional Dyspepsia of Liver Stagnation and Spleen Deficiency

目的评价中医加味逍遥散治疗肝郁脾虚型功能性消化不良的临床效果.方法根据随机数字表法,将64例功能性消化不良患者分为中医组和西医组分别进行对应治疗,时间以2017年1月—2018年12月为准.西医组以多潘立酮和复方消化酶胶囊治疗,中医组根据辨证分型以加味逍遥散治疗.对比两种疗效数据、不良反应数据及复发数据.结果中医组疗效为96.87%与西医组疗效的90.63%比较,两组差异无统计学意义(x^2=1.0667,P>0.05).中医组不良反应发生率为0.00%,西医组不良反应发生率为12.50%,中医组明显更少,差异有统计学意义(x^2=4.2667,P<0.05).随访2个月,两组复发率比较,中医组为3.13%,明显少于西医组的18.75%(x^2=4.0100,P<0.05).结论针对功能性消化不良可采用中医辨证方法,以加味逍遥散治疗肝郁脾虚证型,不但治疗效果好,且安全性高,复发率少,值得推广.

Objective To evaluate the clinical effect of TCM Jiawei Xiaoyao Powder in the treatment of functional dyspepsia of liver stagnation and spleen deficiency. Methods According to the random number table method, 64 patients with functional dyspepsia admitted to our hospital from January 2017 to December 2018 were divided into two groups: the Chinese medicine group and the western medicine group. The western medicine group was treated with domperidone and compound digestive enzyme capsules, and the Chinese medicine group was treated with Jiawei Xiaoyao Powder according to syndrome differentiation. The efficacy, adverse reaction and recurrence in the two groups were compared. Results The efficacy of the Chinese medicine group was 96.87%, and was 90.63% in the Western medicine group. There was no significant difference between the two groups (χ^2=1.066 7, P>0.05). The incidence of adverse reactions in the Chinese medicine group was 0.00%, which was significantly lower than that in the Western medicine group (12.50%)(χ^2=4.266 7, P<0.05). After 2 months of follow-up, the recurrence rate of the Chinese medicine group was 3.13%, which was significantly lower than that in the Western medicine group (18.75%)(χ^2=4.010 0, P<0.05). Conclusion For functional dyspepsia, TCM syndrome differentiation method can be used. The efffect of Jiawei Xiaoyao Powder is significant in the treatment of liver stagnation and spleen deficiency syndrome. It has good therapeutic effect, high safety and less recurrence rate. It is worthy of promotion.