预注右旋美托咪啶用于喉显微手术麻醉的临床效果分析

Clinical Effect Analysis of Preinjection Dexmedetomidine for Laryngeal Microsurgery Anesthesia

目的探讨预注右旋美托咪啶用于喉显微手术麻醉的临床效果.方法选定2016年11月—2018年11月到该院接受治疗的30例喉显微手术麻醉患者,随机分为对照组15例(安慰剂)与观察组15例(右旋美托咪啶),比较两组各阶段心率(HR)、平均动脉压(MAP)指标、不良反应发生率、离开手术室时间、完全清醒时间及轻拍睁眼时间指标.结果治疗结束,观察组在T0、T1、T2、T3阶段的HR、MAP指标上均低于对照组(P<0.05);观察组不良反应发生率(13.33%)指标明显低于对照组(46.67%)(x^2=3.968,P<0.05);观察组离开手术室时间、完全清醒时间及轻拍睁眼时间均低于对照组(t=4.086,5.982,12.350,P<0.05).结论右旋美托咪啶方法可有效降低喉显微手术麻醉患者不良反应发生率,值得推广使用.

Objective To investigate the clinical effect of pre-filled dexmedetomidine for laryngeal microsurgery. Methods Thirty patients with laryngeal microsurgery who underwent treatment from November 2016 to November 2018 were randomly assigned to 15 patients in the control group (placebo) and 15 patients in the observation group (dexmedetomidine). The heart rate (HR), mean arterial pressure (MAP) index, incidence of adverse reactions, time to leave the operating room, full waking time, and pat squint time were compared between the two groups. Results At the end of treatment, the HR and MAP indexes of the observation group at T0, T1, T2, and T3 were lower than those of the control group (P<0.05). The incidence of adverse reactions in the observation group (13.33%) was significantly lower than that in the control group (46.67%)(χ^2=3.968,P<0.05). The time of leaving the operating room, the time of complete waking, and the time of tapping the eye in the observation group were lower than those in the control group (t=4.086, 5.982, 12.350,P<0.05). Conclusion The dexmedetomidine method can effectively reduce the incidence of adverse reactions in patients undergoing laryngeal microsurgery and is worthy of popularization.