甲羟孕酮联合宫腔镜手术治疗子宫内膜息肉的临床效果观察

Clinical effects of medroxyprogesterone combined with hysteroscopic surgery in treatment of endometrial polyp

目的:探讨甲羟孕酮联合宫腔镜手术治疗子宫内膜息肉(EP)的临床价值。方法:将98例EP患者按抽签方式分为研究组(n=49)与对照组(n=49)。对照组施行宫腔镜手术治疗,研究组接受甲羟孕酮联合宫腔镜手术治疗,比较两组月经量、子宫内膜厚度、月经周期恢复正常比例、复发率。结果:治疗后,两组PBAC评分、子宫内膜厚度均显著下降,其中研究组变化幅度更大,差异具有统计学意义(P<0.05);与对照组相比,研究组月经周期恢复正常比例更高,复发率更低,差异具有统计学意义(P<0.05)。结论:甲羟孕酮联合宫腔镜手术治疗EP安全有效。

Objective:To investigate the clinical value of medroxyprogesterone combined with hysteroscopic surgery in treatment of endometrial polyp(EP).Methods:98 EP patients were divided into research group(n=49)and control group(n=49)by draw lots.Control group was given hysteroscopic surgery,while research group was treated with medroxyprogesterone and hysteroscopic surgery.The menstrual blood volume,endometrial thickness,rate of recovering to normal menstrual cycle,recurrence rate were compared between the two groups.Results:After treatment,the PBAC score and endometrial thickness in the two groups significantly decreased,and the changing range of research group was larger(P<0.05);Compared with control group,the rate of recovering to normal menstrual cycle in research group was higher,while the recurrence rate in research group was lower(P<0.05).Conclusion:Medroxyprogesterone combined with hysteroscopic surgery in treatment of EP is safe and effective.