生长素联合左旋咪唑对重型肝炎患者血浆细胞因子及肝纤维化指标的影响

Effects of Auxin Combined with Levamisole on Plasma Cytokines and Liver Fibrosis in Patients with Severe Hepatitis

目的:探究生长素联合左旋咪唑对重型肝炎患者血浆细胞因子及肝纤维化指标的影响。方法:选取2017年6月-2018年6月本院收治的重型肝炎患者100例,按照随机数字表法分成对照组与研究组,各50例。对照组采用生长素治疗,研究组采用生长素联合左旋咪唑治疗。对比两组的血浆细胞因子、肝纤维化指标以及治疗效果。结果:治疗后,研究组各项血浆细胞因子均优于对照组(P<0.05);研究组各肝纤维化指标均优于对照组(P<0.05);研究组治疗总有效率高于对照组(P<0.05)。结论:使用生长素联合左旋咪唑治疗重型肝炎,能够明显改善患者的血浆细胞因子和肝纤维化指标,改善治疗效果,提升患者的生活质量,应当在临床中进一步推广。

Objective:To explore the effect of Auxin combined with Levamisole on plasma cytokines and liver fibrosis in patients with severe hepatitis.Method:100 patients with severe hepatitis admitted to our hospital from June 2017 to June 2018 were selected,they were divided into control group and study group according to random number table method,50 cases in each group.The control group was treated with Auxin and the study group was treated with Auxin combined with Levamisole.The plasma cytokines,liver fibrosis index and therapeutic effect were compared between the two groups.Result:After treatment,all plasma cytokines in the study group were better than those in the control group(P<0.05).The each indexes of liver fibrosis in the study group were better than those in the control group(P<0.05).And the total effective rate in the study group was higher than that in the control group(P<0.05).Conclusion:In the treatment of severe hepatitis,auxin combined with levamisole can significantly improve the plasma cytokines and liver fibrosis indexes,improve the therapeutic effect and improve the quality of life of patients,it should be further promoted in clinical practice.