新生儿休克及影响预后的相关指标分析

Analysis of Neonatal Shock and Related Indicators Affecting Prognosis

目的:研究新生儿休克及影响预后的相关指标。方法:选取2017年4月-2018年4月本院收治的休克患儿87例,均监测其生命体征,给予治疗,收集并记录相关指标。根据期预后情况将其分为预后良好组和预后不良组,比较不同预后患儿的相关指标、出生后白细胞及C反应蛋白、临床症状情况。结果:本组患儿经治疗预后良好61例,预后不良26例;不同预后患儿胎龄、阿氏评分、随机血糖指标比较,差异均无统计学意义(P>0.05),预后不良组pH值、BE值均低于预后良好组,乳酸水平高于预后良好组,差异均有统计学意义(P<0.05);不同预后患儿娩出即刻、24 h后白细胞及C反应蛋白比较,差异均无统计学意义(P>0.05);不同预后患儿感染、羊水污染、宫内窘迫、肺出血症状发生率比较,差异均无统计学意义(P>0.05),预后不良组多器官衰竭、呼吸系统衰竭发生率均高于预后良好组(P<0.05)。结论:新生儿休克预后与pH值、BE值、乳酸、多器官衰竭、呼吸系统衰竭具有密切联系,可通过上述指标对患儿预后情况予以评估,为临床治疗提供参考,保障患儿的生命安全。

Objective:To study the neonatal shock and related prognostic indicators.Method:A total of 87 children with shock admitted to our hospital from April 2017 to April 2018 were selected.Their vital signs were monitored and treated.Relevant indicators were collected and recorded.According to the prognosis,they were divided into good prognosis group and bad prognosis group.Relevant indicators,postnatal white blood cells,C-reactive protein and clinical symptoms of children with different prognosis were compared.Result:In this group,61 cases had good prognosis and 26 cases had poor prognosis after treatment.The gestational age,Apgar score and random blood glucose index in children with different prognosis were compared,the differences were not statistically significant(P>0.05).The pH value and BE value in poor prognosis group were lower than those of good prognosis group,and the lactate level was higher than that of good prognosis group,the differences were statistically significant(P<0.05).The white blood cells and C-reactive protein in children with different prognosis immediately after delivery and 24 hours after delivery were compared,the differences were not statistically significant(P>0.05).The incidence of infection,amniotic fluid pollution,intrauterine distress and pulmonary hemorrhage in children with different prognosis were compared,the differences were not statistically significant(P>0.05).The incidence of multiple organ failure and respiratory failure in poor prognosis group were higher than those of good prognosis group(P<0.05).Conclusion:The prognosis of neonatal shock is closely related to pH value,BE value,lactic acid,multiple organ failure and respiratory failure,the prognosis of neonatal shock can be evaluated by the above indicators,which can provide reference for clinical treatment and ensure the life safety of neonates.