CT影像组学在孤立性肺结节中的研究进展

Advances of Radiomics Research Based on Computed Tomography in Solitary Pulmonary Nodules

随着计算机断层扫描在肺癌筛查中的广泛应用,孤立性肺结节的发现率较以往显著上升,但其良恶性鉴别和侵袭性评估等仍是近年来胸部影像学研究的热点及难点。影像组学可以从医学影像图像中高通量地提取并分析大量高级且定量的影像学特征,对疾病的良恶性定性诊断、分期、预后预测、疗效评价等具有重要价值。本文介绍了孤立性肺结节的传统CT特征和影像组学基本流程,并对影像组学在孤立性肺结节的良恶性鉴别、侵袭性评估等方面的研究进展进行综述。

With the wide application of computed tomography(CT)in lung cancer screening,the discovery rate of solitary pulmonary nodules is significantly higher than before,but its benign and malignant identification and invasiveness evaluation are still hot and difficult topic in chest imaging research in recent years.Radiomics can extract and analyze a large number of high-level and quantitative imaging features from medical image images,which is of great value for qualitative diagnosis,staging,prognosis prediction and therapeutic evaluation of diseases.This article introduces the traditional CT features of solitary pulmonary nodules and the basic flow of radiomics,then reviews the research progress of radiomics in the benign and malignant identification and invasiveness evaluation of solitary pulmonary nodules.