莫西沙星在经直肠前列腺穿刺活检中的应用

The feasibility and safety of applying moxifloxacin in transrectal biopsy of prostate

目的初步探讨莫西沙星在经直肠前列腺穿刺活检中的有效性和安全性。方法回顾性分析了29例使用莫西沙星预防性应用抗生素的经直肠前列腺穿刺病例,观察有无发热等前列腺穿刺相关并发症的发生以及有无药物不良反应。结果穿刺后无一例出现发热,出现急性尿潴留1例(3.4%),出现轻度肉眼血尿16例(55.2%)。有2例(6.9%)患者诉轻度上腹部不适、恶心感。结论莫西沙星可作为经直肠前列腺穿刺活检的预防性抗生素,并且安全有效。

Objective To investigate the efficacy and safety of applying moxifloxacin in transrectal biopsy of prostate. Methods A retrospective analysis was carried out on the efficacy and safety of moxifloxacin as prophylactic antibiotic for 29 patients who received transrectal biopsy of prostate. Complications such as fever relative to biopsy and any adverse reactions of moxifloxacin were analyzed. Results All patients received the examinations successfully. No fever occurred in the patients after biopsy, acute urinary retention appeared in 1 case (3.4%), mild gross hematuria in 16 cases (55.2%), and mild upper abdominal discomfort and nausea in two patients (6.9%). Conclusion Moxifloxacin can be used as a prophylactic antibiotic for transrectal biopsy of prostate and it is safe and effective.