成人阻塞性睡眠呼吸暂停综合征患者认知功能障碍的诊断及治疗研究进展

Diagnosis and treatment of cognitive deficits in adult patients with obstructive sleep apnea hypopnea syndrome

阻塞性睡眠呼吸暂停综合征(OSAS)是一种发病率较高的睡眠及呼吸障碍性疾病,可对全身多系统及器官产生损害。近年研究发现,OSAS可导致认知功能障碍,但其具体发病机制尚不明确,可能与慢性间歇低氧、睡眠结构紊乱等有关。认知功能障碍对OSAS患者的生活及工作产生了诸多不利影响。对OSAS伴发的认知功能障碍进行早期诊断及治疗对认知功能障碍的改善具有积极意义。

Sleep apnea hypopnea syndrome (OSAS) is a sleep and respiratory disorder with high incidence, which can cause damage to multiple systems and organs. Several studies have shown that OSAS mainly leads to cognitive impairment;however, the specific mechanism is not clear. Cognitive impairment may be because of chronic intermittent hypoxia, sleep disorders, etc.;this can seriously affect the quality of life. Early diagnosis and treatment of OSAS significantly improves the cognitive impairment in patients with OSAS and cognitive deficits.