幽门螺杆菌与血液系统疾病的研究进展

Research Progress of Relationship Between Helicobacter Pylori and Hematonosis

幽门螺杆菌(Hp)感染是慢性胃炎、消化道溃疡、胃癌等消化系统疾病的主要病因,但多项研究表明,感染Hp的人群缺铁性贫血、免疫性血小板减少症、黏膜相关组织淋巴瘤等血液系统疾病的发病率较未感染的人群高,可见Hp在血液系统疾病中也起重要作用。其中CD4+T细胞在Hp感染相关疾病的诱导中起基础性作用。随着人们饮食结构和生活习惯的改变,Hp的感染率逐渐升高。因此及早发现Hp感染,在进行对症治疗的同时清除Hp,对提高血液系统疾病的治疗效果具有重要意义。

Helicobacter pylori(Hp)infection is the main cause of chronic gastritis,peptic ulcer,gastric cancer and other digestive diseases.However,some studies have shown that population infected with Hp have a higher incidence of hematological system disease such as iron deficiency anemia,immune thrombocytopenia,mucosa-associated lymphoid tissue lymphoma than the uninfected population,suggesting that helicobacter pylori also plays an important role in hematonosis.With the change of people,s diet and living habits,the infection rate of Hp gradually increases.Therefore,early detection and eradication of Hp infection is of great significance for reducing the incidence of hematonosis.