药物涂层球囊治疗下肢动脉粥样硬化闭塞性疾病的疗效评价

Efficacy evaluation of drug-coated balloon therapy in treating patients with atherosclerotic occlusive disease of lower extremity

目的探讨药物涂层球囊治疗下肢动脉粥样硬化闭塞性疾病的疗效。方法回顾性分析接受药物涂层球囊治疗的38例下肢动脉硬化闭塞性疾病患者的术前、术中以及术后随访资料。结果本研究38例患者患肢血管均再通成功,术后随访期间均未发生与手术相关或其他原因导致的死亡、截肢、靶病变血栓形成等并发症,无需要手术再干预患者,随访率100.00%。术后6个月、1年的Ⅰ期通畅率为84.21%、73.68%。所有患者术后不同时点的踝肱指数(ABI)、行走距离、Rutherford分级均较术前显著改善(P<0.05)。结论药物涂层球囊治疗下肢动脉粥样硬化闭塞性疾病的疗效显著。

Objective To explore the efficacy of drug-coated balloon therapy in treatment of patients with atherosclerotic occlusive disease of lower extremity.Methods The preoperative,intra-operative and postoperative follow-up data of 38 patients with arteriosclerosis occlusive disease of lower extremity treated by drug-coated balloon therapy were retrospectively analyzed.Results All the 38 patients had successful revascularization of affected limbs.During the follow-up period,no complications such as death,amputation,thrombosis of target lesions and other complications associated with surgery occurred.No patients with further intervention were observed,and the follow-up rate was 100.00%.The patency rate of stageⅠwas 84.21%and 73.68%at 6 months and 1 year after operation.Ankle Brachial Index(ABI),walking distance and Rutherford grading of all patients at different time points after operation were significantly improved when compared with those before operation(P<0.05).Conclusion Drug-coated balloon therapy is effective in the treatment of patients with atherosclerotic occlusive diseases of lower extremity.