盐酸坦洛新缓释片联合体外冲击波碎石术治疗5～10 mm单侧输尿管结石的疗效观察

Efficacy observation of tamsulosin hydrochloride sustained-release tablets combined with extracorporeal shock wave lithotripsy in treating patients with 5 to 10 mm unilateral ureteral calculi

目的 探讨盐酸坦洛新缓释片联合体外冲击波碎石术治疗5~10mm单侧输尿管结石的临床疗效。方法 选取80例5~10mm单侧输尿管结石患者,按照治疗方式分为2组。对照组采用体外冲击波碎石术治疗,观察组采用体外冲击波碎石术联合盐酸坦洛新缓释片治疗,比较2组的治疗效果。结果 观察组患者结石排净率显著高于对照组(P<0.05),排石时间显著短于对照组(P<0.05)。观察组患者肾绞痛发生率显著低于对照组(P<0.05)。术后1个月,观察组疼痛程度评分显著低于对照组(P<0.05)。结论 对5~10mm单侧输尿管结石患者行盐酸坦洛新缓释片联合体外冲击波碎石术治疗的效果理想,有利于提高结石排净率。

Objective To investigate the clinical efficacy of tamsulosin hydrochloride sustained-release tablets combined with extracorporeal shock wave lithotripsy in treating patients with 5 to 10 mm unilateral ureteral calculi.Methods Eighty patients with 5 to 10 mm unilateral ureteral calculi were selected and divided into two groups according to therapeutic methods.Patients in the control group were treated with extracorporeal shock wave lithotripsy,and patients in the observation group were treated with tamsulosin hydrochloride sustained-release tablets and extracorporeal shock wave lithotripsy.The effects were compared between the two groups.Results The stone clearance rate of the observation group was significantly higher than that of the control group(P<0.05),and the stone clearance time was significantly shorter than that of the control group(P<0.05).The incidence of renal colic in the observation group was significantly lower than that in the control group(P<0.05).One month after operation,the pain score of the observation group was significantly lower than that of the control group(P<0.05).Conclusion The tamsulosin hydrochloride sustained-release tablets combined with extracorporeal shock wave lithotripsy is effective in treating patients with 5 to 10 mm unilateral ureteral calculi,and it is helpful to improve the stone removal rate.