血液肿瘤患者PICC置管后首次换药时间研究

Study on first dressing change time after PICC placement among patients with hematological malignancy

目的探讨首次换药时间对血液肿瘤患者PICC置管后穿刺点愈合及并发症的影响。方法将117例血液肿瘤PICC置管患者随机分成对照组60例和观察组57例,对照组在PICC置管后24h常规进行首次换药,观察组则在术后48h首次换药,比较两组置管后穿刺点渗血、感染及愈合情况。结果两组置管后穿刺点愈合较好率及换药次数比较,差异有统计学意义(均P<0.01)。结论血液肿瘤患者PICC置管后48h首次换药,可促进穿刺点愈合,减少换药次数,减轻患者痛苦。

Objective To explore the efficacy of extending the interval of first-time dressing change in such PICC related outcomes as healing rate of puncture site and complications among patients with hematological malignancy.Methods Totally,117 hematological malignancy patients were randomly assigned to a control group(n=60),who received first dressing change at 24 h after PICC insertion,and an intervention group(n=57),who received first dressing change at 48 h.Rates of slight bleeding,infections,and healing at puncture site were compared between the 2 groups.Results The rates of excellent healing at puncture site,and the counts of dressing change had significant differences between the 2 groups(P<0.01 for both).Conclusion Extending the interval of first time dressing change to 48 h after PICC insertion could promote wound healing and reduce dressing change frequencies in patients with hematological malignancy.