药学干预对喹诺酮类药物临床应用效果分析

Pharmaceutical Intervention on Clinical Application of Quinolones

目的 研究探讨药学干预对喹诺酮类药物临床应用的效果。方法 选择我院应用喹诺酮类抗菌药物治疗的120例患者(2018年1月~2018年12月),随机划分为2组(60例/组),对照组由医护人员开展用药指导,观察组实施由临床药师主导的药学干预,比较用药依从性、用药认知度评分、喹诺酮类药物不合理应用率、用药频度、药物利用指数、满意度。结果 ①观察组的用药总依从率、总满意率均较对照组更高(P <0.05)。②干预后,观察组的用药认知度评分较对照组更高( P <0.05),其喹诺酮类药物不合理应用率、用药频度、药物利用指数均较对照组更低( P <0.05)。结论 药学干预可有效提高喹诺酮类抗菌药物在临床上的合理应用率,还可提高患者的用药依从性和认知度,使患者对临床用药服务更加满意。

OBJECTIVE To study the effect of pharmaceutical intervention on cl inical application of quinolones. METHODS 120 patients (Janu ary 2018 to Decemb er 2018) treated with quinolone antibiotics in our hospital were randomly divide d into two groups (60 cases/group).The control group was guided by medical sta ff,while the observation group was guided by clinical pharmacists.Comparison s were made on drug compliance,drug recognition score,unreasonable use rate o f quinolones,drug frequency and drug use.Use index,satisfaction. RESULT S (1) The total compliance rate and satisfaction rate of the observation group were h igher than those of the control group ( P <0.05).(2)After the intervention, the cognitive score of the observation group was higher than that of the control group ( P <0.05),and the irrational rate,frequency and index of drug use of quinolones in the observation group were lower than those in the control group ( P <0.05). CONCLUSION Pharmaceutical interven tion can effectively improve the rational application rate of quinolone antibiotics in clinic.It can also impr ove the compliance and recognition of patients,and make patients more satisfie d with clinical medication services.