结直肠癌肝转移:如何合理的选择切除与消融治疗

How to select ablation or resection reasonably for curative treatment of patients with colorectal liver metastases

肝转移的手术切除是结直肠癌肝转移患者获得长期生存的最佳治疗手段,而消融治疗具有创伤小、恢复快的优点,随着技术的进步其有效性和安全性也逐步得到认可。在临床实践中,如何合理选择这两种治疗手段尚存在一些争议。本综述的目的是通过文献回顾,探讨消融治疗在不可切除的结直肠癌肝转移中的作用,以及技术上可切除的肝转移选择消融对比切除的疗效,进而明确消融治疗的有效性和局限性,为临床实践的选择提供帮助。

Surgical resection of liver metastase is the first-line treatment for patients with color-ectal liver metastasis (CRLM) providing potential curative intent of long-term survival, while ab-lation can be used for small CRLM achieving comparable survival results with the advantages of minimal trauma and rapid recovery. However, how to select ablation or resection reasonably is unclear in clinical practice sometimes. The purpose of this review is to explore the role of ablation in liver metastasis of unresectable colorectal liver metastases and compare the survival results in technically resectable patients receiving either liver resection or ablation through literature review, so as to clarify the effectiveness and limitations of ablation therapy, and to help doctors for the selection between the two methods in clinical practice.