摘要
基因编辑技术是人为的对基因片段进行修改的一种技术。新型基因编辑技术关注在人工核酸酶剪切技术领域,主要为 ZFN 技术,TALEN 技术,CRISPR 技术以及单碱基编辑技术。基因编辑技术的不断完善促进了农业,畜牧业和生物医学等领域的快速发展,但与此同时,技术缺陷和伦理争议也为其自身的发展带来了巨大的挑战。本文将对基因编辑技术的发展与挑战,以及国内外的伦理探讨进行简要综述,期望能启发读者重新认识基因编辑技术。
Gene editing is a technique for modifying gene fragments. The novel gene editing technology focuses on the field of artificial nuclease cleavage technology, mainly ZFN technology, TALEN technology, CRISPR technology and base editing technology. The continuous improvement of gene editing technology has promoted the rapid development of agriculture, animal husbandry and biomedicine, but at the same time, technical defects and ethical controversy have brought enormous challenges to its own development. This article will briefly discuss the development and challenges of gene editing technology, as well as the views at home and abroad, and hope to inspire readers to recognize gene editing technology.
作者
刘耀
熊莹喆
蔡镇泽
张冰
Yao Liu;Yingzhe Xiong;Zhenze Cai;Bing Zhang(Sports and Health Science Research Center, Tsinghua University, Beijing 100084, China)
出处
《生物工程学报》
CAS
CSCD
北大核心
2019年第8期1401-1410,共10页
Chinese Journal of Biotechnology
基金
中国高等教育学高等教育科学研究“十三五”教育科学规划课题(No.17TY021)资助~~
关键词
基因编辑技术
发展
挑战
伦理学限制
genetic editing technology
development
challenge
ethical limitations