一例发热伴血小板减少综合征病例的流行病学调查

Epidemiological investigation on a case of fever with thrombocytopenia syndrome

【目的】分析发热伴血小板减少综合征(SFTS)病例的流行病学特征,为制定该病的防控对策提供依据。【方法】对浙江省永康市1例发热、腹泻,同时伴血小板减少的病例进行流行病学调查及实验室检测。【结果】该病例居住在丘陵山区,居住地区有适宜蜱生存的环境,家中饲养的狗有媒介寄生蜱,潜伏期内有野外作业史,虽无明确的蜱叮咬史,但有帮狗徒手抓灭蜱的习惯。病例血样经PCR病毒核酸检测,结果为发热伴血小板减少综合征布尼亚病毒核酸阳性,根据病例临床表现和实验室检查结果,确诊为SFTS病例。病例搜索未发现其他病例。【结论】目前尚没有SFTS有效的治疗药物和疫苗,应采取综合的预防控制措施。

[Objective] To analyze the epidemiological characteristics of cases with fever and thrombocytopenia syndrome(SFTS) and provide the basis for the formulation of prevention and control measures for the disease in Yongkang City.[Methods] Describing epidemiology and case investigation were conducted.[Results] The patient lived in a hilly area where there was a suitable environment for the survival of ticks,and the dogs raised at home had a vector parasitic cricket.There was a history of field operations during the incubation period. The patient had no clear history of insect bites,yet with a habit of helping dogs to arrest ticks with hands.The blood sample of the patient was detected by PCR virus nucleic acid test.The result was that the fever was combined with thrombocytopenia.The nucleic acid of Bunia virus was positive.Based on the clinical performance of the case and the results of the laboratory examination,the case was diagnosed as SFTS.No additional cases were found.[Conclusion] At present,there have not been effective drugs and vaccines for SFTS;therefore,it is imperative to take comprehensive preventive and control measures against it.