小肠黏膜下层预防腮腺良性肿瘤术后味觉出汗综合征的疗效观察

Therapeutic Effect of Small Intestinal Submucosa in Preventing Frey’s Syndrome after Surgery of Parotid Benign Tumor

目的:观察与评价小肠黏膜下层补片用于腮腺良性肿瘤预防术后味觉出汗综合征的临床效果。方法:选择63例腮腺良性肿瘤患者,根据患者术前意愿分为小肠黏膜下层补片治疗的观察组(32例)和无补片治疗的对照组(31例)。术后随访6~18个月,统计术后异物感情况,采取主观评价与客观评价的方法判断术后味觉出汗综合征的发生情况。结果:术后观察组与对照组患者味觉出汗综合征的主观评价阳性率分别为0%、19.35%,客观评价的阳性率分别为3.13%、48.39%,两组间相比,观察组均优于对照组,差异有统计学意义(P<0.05);术后异物感的两组间比较,差异无统计学意义(P>0.05)。结论:术中植入小肠黏膜下层补片可有效预防腮腺良性肿瘤术后味觉出汗综合征的发生,且方法简单,术后患者感觉舒适,值得临床推广使用。

Objective:To observe and evaluate the effect of small intestinal submucosa in preventing Frey's syndrome after surgery of parotid benign tumor.Methods:A total of 63 patients with benign parotid tumors were divided to two groups according to their inclination.The observation group used small intestinal submucosa after surgery while control group did not.There were 32 cases in the observation group and 31 cases in the control group.All cases were followed up 6 to 18 months after surgery to analyze the occurrence of Frey's syndrome and foreign body feeling.The occurrence of Frey's syndrome was evaluated by subjectively and objectively ways.Results:Positive rates of subjective evaluation were 0% in the observation group and 19.35% in the control group,and the positive rates of objective evaluation in two groups were 3.13% and 48.39%,respectively.The observation group was superior to the control group ( P <0.05).There was no significant difference in the foreign body sensation between two groups ( P >0.05).Conclusion:Using small intestinal submucosa patch in parotid benign tumor can effectively prevent the occurrence of Frey's syndrome after surgery,which is simple,comfortable and worthy of spread.